Examples:

• Are you sure an ambulance is not the best idea?
• Are you sure about this, with everything that's going on?
• Are you sure what we're doing is a good idea?
• Are you sure that this guy's even in the city?
• Are you sure this is the right moment, Mr. Newton?
• Are you sure you know a way to find Avexis?
• Are you sure your victim was one of our guests?
• Are you sure we can't sleep in the car?
• Are you sure that it was here at the Montecito?
• Are you sure this is the way to New Orleans?