Macule [noun]

Definition of Macule:

dirt smear

Synonyms of Macule:

● Blot

● Spot

● Smut

● Blur

● Soiled spot

Opposite/Antonyms of Macule:

● Cleanliness

Sentence/Example of Macule:

This macule, plaque, or patch of diseased integument is in its typical features characteristic.